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KMID : 1094020090260030279
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Journal of Veterinary Clinics
2009 Volume.26 No. 3 p.279 ~ p.281
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Amyloid-producing Odontogenic Tumor in Two Do
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Kim Hyung-Jin
Kang Min-Soo
Oh Won-Seok
Kim Eun-Ok
Lee Woo-Yeal
Kim Eun-Young
Kim Dae-Yong
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Abstract
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Amyloid-producing odontogenic tumors were described in the gingival masses of two Maltese dogs. Gingival masses were surgically removed and submitted for diagnosis. On histopathology, the masses were poorly demarcated, infiltrative, and consisted of cuboidal and columnar epithelial cells with palisading pattern. Nodular deposit of congophilic amyloid-like material and mineralization were another features of the tumors. Immunohistochemically, the neoplasticd cells were positive to pancytokeratin and neuron-specific enolase but were negative to vimentin. The amorphous homogeneous eosinophilic materials were positive to Congo red stain and showed apple-green color under the polarized microscope. Based on these results, both cases were diagnosed as amyloid-producing odontogenic tumors in dogs.
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KEYWORD
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amyloid, APOT, gingival mass, tumor, dog
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